My interest in nootropics has been resparked lately. Other than Piracetam I don't have much experience with them yet though. So I ordered a few and I tried Sulbutiamine first, because the documented effects of this got me interested: moodlift, euphoria, energy, memory improvement, antidepressive/antifear/antishyness qualities.
I took 201 mg in a bit of coffee. It masked the (pretty nasty) taste very well. I was definitely noticing things after the 30 minute mark. I felt distinctly uplifted and caffeinated (I had some coffee and it felt enhanced). I also was sharper and wittier. My eyes tended to drift slightly out of focus though. I was feeling kind of superior, not to others but to my regular self. Don't know if it was the coffee or the Sul, but I noticed some diuretic effect. And improved sense of smell. And less coughing (remnants from a recent flu).
Well, colour me impressed; I went for an errand and I was so much merrier and outgoing instead of more towards grumpy and introverted. My mind seemed very clear, yet, by lack of a better description, occupied at the same time (I almost forgot to take a cart in the store).
Some long duration (at least 12 hours). I'm not sure if the slow decline started around T+8, if there ever was one, it started about then. This material is actually pretty wonderful. It definitely touches dopamine in some way (it apparently 'traps' it). Pretty good for a vitamin B1 derivative. Hail to the Japanese.